Computer Visualization of Long Genomic Sequences.

Dachywan Wu, Jie Lin, Lakshmi Subbiah, Stephen Hou.

 
Department of Computer Science and Applied Mathematics & 
Department of Biological, Chemical and Physical Sciences 
Illinois Institute of Technology, Chicago, IL 60616.

---

Introduction

<-- Click on the wcurve to see w-curve vertical 30 degree rotation in 3D.(Produced from the Silicon Graphics)

We have been visualizing some important genomic subsequences with a novel numerical mapping algorithm, the W-Curve. The W-Curve is Y projection of the Genomic Chaos Representation, onto a Z axis, where Z is the 5' to 3' nucleotide position. The W-Curve presents compact visual informational topology of biologically significant local and global genomic sequences. These projections reveal important embedded DNA patterns without any priori knowledge about their location or biological significance. W-Curve are useful for visually categorizing long strings of DNA and analyzing the molecular evolution of well studied gene families, especially the evolution of HIV-1 virus. In this website, we will show you step by step how you can generate a pylogenetic tree from a basic gene sequence which you can download freely from GenBank.

---

Click here if you are on SGI UNIX

Click here if you are on Windows/Dos

Related Site:

For other publications, algorithms and research relating to Computer Science using biological models, see the following URL's:

Evolution Scheduling & Evolving Processes

Visualization of Biological Sequence Similarity Search Results

http://140.129.66.15

Chinese Fonts (big-5) needed in the last site. Click here to obtain a free Chinese translator

About this project...